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BULLOUS PEMPHIGOID ANTIGEN 1
Descriptors Found:
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DeCS
Descriptor
English
:
Dystonin
Descriptor
Spanish
:
Distonina
Descriptor
Portuguese
:
Distonina
Synonyms
English
:
230 kDa Bullous Pemphigoid Antigen
230-240 kDa Bullous Pemphigoid Antigen
Bullous Pemphigoid Antigen 1
Hemidesmosomal Plaque Protein
230 240 kDa Bullous Pemphigoid Antigen
Tree Number:
D12.776.220.790.625
Definition
English
:
A plakin characterized by repeat sequences homologous to
SPECTRIN
and
PLECTIN
and C-terminal
EF HAND MOTIFS
. It functions as an integrator of
INTERMEDIATE FILAMENTS
, ACTIN and
MICROTUBULES
in
cytoskeleton
networks. It is required for anchoring
intermediate filaments
to the
actin cytoskeleton
in neural and
muscle cells
as well as anchoring KERATIN-containing
intermediate filaments
to
HEMIDESMOSOMES
in
EPITHELIAL CELLS.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56594
Unique Identifier:
D000071821
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS